Agelity
It is a naturally occurring substance. It belongs to the group of inositols. They are a class of compounds that consists of nine distinct isomers. Inositols resemble six-member ring simple sugars (i.e., glucose) but are not sugars but cyclic sugar alcohols. Inositols are, like simple sugars, a part of the normal human diet and as shown by the available evidence also non-toxic. Research have shown that DCI has distinct and interesting bioactivity, differentiating it from some other inositol. A healthy metabolic ageing ingredient. Play an important role in metabolic regulation and work as insulin sentitizers.
Información Técnica
Appearance:
fine-crystalline powder.
Colour:
White to off-white.
Assay:
min. 98%.
Ensayo (saffranal):
mín. 2%.
Loss on drying:
máx. 5%.
Solubility:
Highly soluble in water.
Taste:
Only slightly sweet, no distinct side- or aftertaste.
Estabilidad:
Stable under normal processing and storage conditions.
Benefits
Anti-depressive effect
Depression is a serious disorder in today's society, with lifetime prevalence estimates of up to 21% of the population in some developed countries.
In the study "Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomised, placebo-controlled trial" patients were randomly assigned to receive either a saffron capsule 30 mg [sun] day (BD) (Group 1) or a placebo capsule (BD) (Group 2) during a 6-week study. At six weeks, Crocus sativus produced a significantly better score on the Hamilton depression rating scale than placebo. The results of this study indicate the efficacy of Crocus sativus in the treatment of mild to moderate depression.
Antioxidant properties and improved vision
The macula of the eye, which is located in the centre of the retina, is the part of our body responsible for the precision and sharpness of our vision.
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Factors such as age or smoking cause the macula to deteriorate, resulting in a loss of sharpness of vision.
Appetite regulator
One of its main characteristics is its ability to reduce appetite thanks to its natural satiety effect. This property helps to control the amount of food eaten and to control weight.
Helps control blood glucose levels (Type 2 Diabetes)
According to a study, D-chiro-inositol helps to lower blood insulin and control blood glucose levels. Diabetes is a global disease and the number of people affected has increased in recent years. It can lead to other harmful health conditions such as blindness, kidney failure, heart attacks, strokes and lower limb amputation.
The WHO projects that diabetes will be the seventh leading cause of death by 2030. However, diabetes is treatable and its consequences can be prevented or delayed with diet, physical activity, medication and regular screening and treatment of complications.
Prolongs and intensifies the tanning of the skin
D-chiro-inositol is a natural substance that intensifies and prolongs skin tanning. It helps to reduce sun-induced skin ageing by activating collagen synthesis. This characteristic means that the active ingredient can be used before sunbathing in sun creams or facial creams and after sun exposure in after-sun creams or creams to prolong tanning.
The results of studies carried out with creams containing INN have shown that tanning is prolonged by up to 50% over time and 30% in intensity, while at the same time reducing the effects of light ageing.
References
[1] Jarret L, Wong EHA, and Smith JA, Insulin Mediators from Rat Skeletal Muscle Have Differential Effects on Insulin-Sensitive Pathways of Intact Adipocytes, Science (1985) 227,533-535.
[2] Larner J, Huang LC, Schwartz CF, Oswald AS, Shen TY, Kinter M, Tang G, and Zeller K, Rat liver insulin mediator which stimulates pyruvate dehydrogenase phosphatase contains galctosamine and D-chiroinositol, Biochem. Biophys. Res. Commun. (1988) 151(3), 1416-1426.
[3] Larner J, Huang LC, Schwartz CF, Oswald AS, Shen TY, Kinter M, Tang G, and Zeller K, Rat liver insulin mediator which stimulates pyruvate dehydrogenase phosphatase contains galctosamine and D-chiroinositol, Biochem. Biophys. Res. Commun. (1988) 151(3), 1416-1426.
[4] Suzuki S, Taneda Y, Hirai S, Abe S, Sasaki A, Suzuki K, and Toyata T, Molecular Mechanism of Insulin Resistance in Spontaneous Diabetic GK(Goto-Kakizaki) Rats, New Directions in Research nd Clinical Works for Obesity and Diabetes Mellitus (1991) ed. Sakamoto N, Angel A, Hotta N., Elsevier Science Publishers, p. 197-203.
[5] Y Pak, HUang LC, Lilley KJ, and Larner J, In Vivo Conversion of [3H] Myoinositol to [3H] chiroinositol in Rat Tissues, J. Biol. Chem. (1992) 267(24), 16904-16910.
